Protein Backbone Torsion Angle-Based Structure Comparison and Secondary Structure Database Web Server
نویسندگان
چکیده
منابع مشابه
Protein Backbone Torsion Angle-Based Structure Comparison and Secondary Structure Database Web Server
Structural information has been a major concern for biological and pharmaceutical studies for its intimate relationship to the function of a protein. Three-dimensional representation of the positions of protein atoms is utilized among many structural information repositories that have been published. The reliability of the torsional system, which represents the native processes of structural ch...
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Every year between 500 and 1000 peptide and protein structures are determined by NMR and deposited into the Protein Data Bank. However, the process of NMR structure determination continues to be a manually intensive and time-consuming task. One of the most tedious and error-prone aspects of this process involves the determination of torsion angle restraints including phi, psi, omega and chi ang...
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This article introduces a novel protein structure alignment method (named TALI) based on protein backbone torsion angle instead of the more traditional distance matrix. Representing protein structure by a serial backbone torsion angles (φ, ψ), protein structure have a simple mapping relationship to protein sequence. Thus, TALI can naturally incorporate sequence information and sequence analysis...
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The recent discoveries of regulatory non-coding RNAs changed our view of RNA as a simple information transfer molecule. Understanding the architecture and function of active RNA molecules requires methods for comparing and analyzing their 3D structures. While structural alignment of short RNAs is achievable in a reasonable amount of time, large structures represent much bigger challenge. Here, ...
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ژورنال
عنوان ژورنال: Genomics & Informatics
سال: 2013
ISSN: 1598-866X,2234-0742
DOI: 10.5808/gi.2013.11.3.155